04-22-2024, 07:42 AM
Suhagra is a medication used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate, which is a phosphodiesterase type 5 (PDE5) inhibitor. The mechanism of action of Suhagra involves several physiological processes:
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- Relaxation of Smooth Muscles: During sexual arousal, nitric oxide (NO) is released from nerve endings in the erectile tissue of the penis. Nitric oxide stimulates the enzyme guanylate cyclase, which increases levels of cyclic guanosine monophosphate (cGMP).
- Increased Blood Flow: Elevated levels of cGMP cause relaxation of the smooth muscles in the penile arteries and corpus cavernosum (spongy erectile tissue). This relaxation allows the arteries to dilate, which increases blood flow to the penis.
- Erection: Suhagra increased blood flow to the penis results in engorgement of the erectile tissue, leading to an erection. Suhagra facilitates this process by inhibiting the enzyme phosphodiesterase type 5 (PDE5).
- PDE5 Inhibition: PDE5 is an enzyme that breaks down cGMP, leading to the cessation of the erection. By inhibiting PDE5, Suhagra prolongs the presence of cGMP in the erectile tissue, enhancing and prolonging the erectile response to sexual stimulation.
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