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Extra Super Vidalista is a combination medication that typically contains two active ingredients: tadalafil and dapoxetine. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor, while dapoxetine is a selective serotonin reuptake inhibitor (SSRI). Each of these components works differently in the body, and they have distinct mechanisms of action. Tadalafil: Tadalafil primarily works by inhibiting the enzyme phosphodiesterase type 5 (PDE5). By inhibiting PDE5, tadalafil increases the levels of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penis. This leads to relaxation of the smooth muscle cells and dilation of the blood vessels, resulting in increased blood flow to the penis during sexual stimulation. This mechanism allows tadalafil to help men achieve and maintain an erection sufficient for sexual activity. Additionally, Extra Super Vidalista may also have effects on smooth muscle cells in other parts of the body, such as the prostate and pulmonary arteries, contributing to its use in treating benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension (PAH), respectively. Dapoxetine: Dapoxetine, on the other hand, is a selective serotonin reuptake inhibitor (SSRI). It primarily works by inhibiting the reuptake of serotonin, a neurotransmitter involved in the regulation of mood and ejaculation. By increasing serotonin levels in the brain, dapoxetine helps to delay the ejaculation reflex, thereby extending the time to ejaculation and improving control over ejaculation timing. This mechanism of action is beneficial in the treatment of premature ejaculation (PE), a common sexual disorder characterized by ejaculation that occurs too quickly during sexual activity. In summary, Extra Super Vidalista combines tadalafil, which promotes the relaxation of smooth muscle cells and increases blood flow to the penis, with dapoxetine, which helps delay ejaculation by affecting serotonin levels in the brain. This combination medication is used to treat both erectile dysfunction and premature ejaculation in men, addressing both aspects of sexual dysfunction simultaneously.